Rapid response

  • Allows for rapid adjustment of depth of analgesia1

Rapid recovery

  • Provides quick emergence for neurological assessment1,2
  • Helps facilitate monitoring of SSEPs3*
    Rapid offset of Remi results in rapid dissipation of analgesic effect within
    5-10 minutes of discontinuation. Other analgesics should be administered prior to discontinuation where postoperative pain is anticipated1

Added characteristics of ULTIVA

  • No accumulation regardless of infusion duration1
  • Can be used in patients with renal or hepatic impairment1
  • Well-established hemodynamic profile1
    In premedicated patients undergoing anesthesia, 1-minute infusions of
    <2 mcg/kg of Remi cause dose-dependent hypotension and bradycardia. When appropriate, bradycardia and hypotension can be reversed by reduction of the rate of infusion of Remi or the dose of concurrent anesthetics, or by the administration of fluids or vasopressors1

Study evaluated patients undergoing spinal surgery.3

Remifentanil is commonly referred to as Remi by anesthesia providers.

Carotid endarterectomy case study

68-year-old male

5'10'', 72 kg (159 lb)

BMI 22.86 kg/m2


  • Coronary artery disease
  • Hypertension
  • Chronic obstructive pulmonary disease (COPD)

Right-hand dominant

Medications: statin, long-acting beta agonist (inhaled), corticosteroid (inhaled), ACE inhibitor, cardioselective beta-blocker, acetylsalicylic acid (withheld for surgery)

This case study is for illustrative and educational purposes only. The dosing regimen is specific to this case study and other regimens may vary depending on patient and procedure. Any use of this product is subject to the judgment of the practitioner in each case. Please consult the full Prescribing Information in the use of this product.



Goal: predictable control

Characteristics of ULTIVA in carotid artery surgery include:

See also:

  1. ULTIVA [package insert]. Rockford, IL: Mylan Institutional LLC; 2016.
  2. Wilhelm W, Schlaich N, Harrer J, et al. Recovery and neurological examination after remifentanil-desflurane or fentanyl-desflurane anaesthesia for carotid artery surgery. Br J Anaesth. 2001;86(1):44-49.
  3. Samra SK, Dy EA, Welch KB, Lovely LK, Graziano GP. Remifentanil- and fentanyl-based anesthesia for intraoperative monitoring of somatosensory evoked potentials. Anesth Analg. 2001;92(6):1510-1515.